(19)

(11)

EP 1 330 549 A2

(12)

(88) Date of publication A3: 01.05.2003 (43) Date of publication: 30.07.2003 Bulletin 2003/31 (21) Application number: 01988454.3 (22) Date of filing: 26.10.2001

(51) International Patent Classification (IPC)7: C12Q 1/68 (86) International application number: PCT/US0150/997 (87) International publication number: WO 0204/6476 (13.06.2002 Gazette 2002/24)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR (30) Priority: 27.10.2000 US 698387 (71) Applicant: ABBOTT LABORATORIES Abbott Park,IL 60064-6050 (US)	(72) Inventors: SOLOMON, Natalie, A. Buffalo Grove, IL 60089 (US) ERICKSON, Dwight, D. Kenosha, WI 53143 (US) ZEIGLER, Sharon, R. Round Lake Beach, IL 60073 (US) (74) Representative: Modiano, Guido, Dr.-Ing. et al Modiano, Josif, Pisanty & Staub,Baaderstrasse 3 80469 München 80469 München (DE)