(19)

(11)

EP 1 334 127 A1

(12)

(43) Date of publication: 13.08.2003 Bulletin 2003/33 (21) Application number: 01980207.3 (22) Date of filing: 01.11.2001

(51) International Patent Classification (IPC)7: C07K 14/535, A61K 47/48, C07K 14/52, C12N 15/63, A61P 7/00, A61K 38/19 (86) International application number: PCT/DK0100/724 (87) International publication number: WO 0203/6626 (10.05.2002 Gazette 2002/19)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 02.11.2000 DK 200001647 (71) Applicants: Maxygen Aps 2970 Hoersholm (DK) Maxygen Holdings Ltd Redwood City, CA 94063 (US)	(72) Inventors: NISSEN, Torben, Lauesgaard,c/o Maxygen ApS DK-2970 Hoersholm (DK) JENSEN, Anne, Dam,c/o Maxygen ApS DK-2970 Hoersholm (DK) (74) Representative: Salka, Jeffrey et al Maxygen ApS,Agern Allé 1,Danish Science Park 2970 Hoersholm 2970 Hoersholm (DK)