(19)

(11)

EP 1 334 128 A2

(12)

(88) Date of publication A3: 03.01.2003 (43) Date of publication: 13.08.2003 Bulletin 2003/33 (21) Application number: 01980206.5 (22) Date of filing: 01.11.2001

(51) International Patent Classification (IPC)7: C07K 14/565, A61K 38/21 (86) International application number: PCT/DK0100/723 (87) International publication number: WO 0203/6628 (10.05.2002 Gazette 2002/19)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 02.11.2000 DK 200001646 (71) Applicant: Maxygen Aps 2970 Hoersholm (DK)	(72) Inventors: BORNAES, Claus DK-2900 Hellerup (DK) ANDERSEN, Kim, Vilbour DK-2700 Broenshoej (DK) RASMUSSEN, Paul, Baad DK-2100 Copenhagen (DK) PEDERSEN, Anders, Hjelholt DK-2800 Lyngby (DK) (74) Representative: Salka, Jeffrey  Maxygen ApS,Agern Allé 1,Danish Science Park 2970 Hoersholm 2970 Hoersholm (DK)