(19)
(11) EP 1 335 899 A2

(12)

(88) Date of publication A3:
14.11.2002

(43) Date of publication:
20.08.2003 Bulletin 2003/34

(21) Application number: 01982452.3

(22) Date of filing: 31.10.2001
(51) International Patent Classification (IPC)7: C07C 233/78, C07C 275/32, C07C 217/58, C07D 239/26, C07D 213/38, C07D 317/58, A61K 31/36, A61K 31/44, A61K 31/165, A61K 31/17, A61P 33/06
(86) International application number:
PCT/EP0112/617
(87) International publication number:
WO 0203/8534 (16.05.2002 Gazette 2002/20)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 10.11.2000 WO PCT/EP00/11142

(71) Applicant: Actelion Pharmaceuticals Ltd.
4123 Allschwil (CH)

(72) Inventors:
  • BOSS, Christoph
    CH-4123 Allschwil (CH)
  • FISCHLI, Walter
    CH-4123 Allschwil (CH)
  • MEYER, Solange
    F-68440 Schlierbach (FR)
  • RICHARD-BILDSTEIN, Sylvia
    F-68170 Rixheim (FR)
  • WELLER, Thomas
    CH-4102 Binningen (CH)

(74) Representative: Kellenberger, Marcus Dr. 
Schönenbuchstrasse 34
4123 Allschwil
4123 Allschwil (CH)

   


(54) SUBSTITUTED ALKYLDIAMINES AS INHIBITORS OF PLASMEPSIN OR RELATED PROTEASES