(19)
(11) EP 1 337 510 A2

(12)

(88) Date of publication A3:
06.03.2003

(43) Date of publication:
27.08.2003 Bulletin 2003/35

(21) Application number: 01994174.9

(22) Date of filing: 06.11.2001
(51) International Patent Classification (IPC)7C07D 201/00
(86) International application number:
PCT/US0147/238
(87) International publication number:
WO 0205/7224 (25.07.2002 Gazette 2002/30)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 06.11.2000 US 246244 P

(71) Applicants:
  • UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Chapel Hill, NC 27599-4105 (US)
  • GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION
    Atlanta, GA 30303 (US)
  • DUKE UNIVERSITY
    Durham, NC 27705 (US)

(72) Inventors:
  • BOYKIN, David
    Atlanta, GA 30315 (US)
  • TIDWELL, Richard, R.
    Pittsboro, NC 27312 (US)
  • WILSON, W., David
    Atlanta, GA 30307 (US)
  • PERFECT, John, R.
    Durham, NC 27707-3813 (US)
  • STEPHENS, Chad, E.
    Villa Rica, GA 30180 (US)

(74) Representative: Reinhard - Skuhra - Weise & Partner GbR 
Postfach 44 01 51
80750 München
80750 München (DE)

   


(54) SYNTHESIS AND ANTIMICROBIAL ACTIVITYOF NOVEL DICATIONIC "REVERSED AMIDINES"