(19)
(11) EP 1 339 731 A1

(12)

(43) Date of publication:
03.09.2003 Bulletin 2003/36

(21) Application number: 01999153.8

(22) Date of filing: 27.11.2001
(51) International Patent Classification (IPC)7C07H 17/08
(86) International application number:
PCT/US0144/423
(87) International publication number:
WO 0206/4608 (22.08.2002 Gazette 2002/34)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 29.11.2000 US 250292 P

(71) Applicant: ACADEMIC PHARMACEUTICALS, INC.
Lake Bluff, IL 60044 (US)

(72) Inventors:
  • SOMBERG, John, C.
    Lake Forest, IL 60645 (US)
  • RANADE, Vasant
    Libertyville, IL 60048 (US)

(74) Representative: Adam, Holger, Dr. 
Kraus & Weisert,Patent- und Rechtsanwälte,Thomas-Wimmer-Ring 15
80539 München
80539 München (DE)

   


(54) SYNTHESIS AND SEPARATION OF OPTICALLY ACTIVE ISOMERS OF ERYTHROMYCIN AND THEIR BIOLOGICAL ACTIONS