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(11)

EP 1 339 748 A2

(12)

(88) Date of publication A3: 05.06.2003 (43) Date of publication: 03.09.2003 Bulletin 2003/36 (21) Application number: 01999578.6 (22) Date of filing: 05.12.2001

(51) International Patent Classification (IPC)7: C07K 14/705, C12N 15/12, C12N 1/21, C12N 5/10, A01K 67/027, C12N 15/00, C07K 16/28, C12Q 1/68, A61K 38/17, G01N 33/68 (86) International application number: PCT/US0146/659 (87) International publication number: WO 0204/6230 (13.06.2002 Gazette 2002/24)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 08.12.2000 US 254323 P 13.12.2000 US 255564 P 21.12.2000 US 257716 P 19.01.2001 US 262848 P (71) Applicant: Incyte Genomics, Inc. Palo Alto, CA 94304 (US)

(72) Inventors: KALLICK, Deborah, A. Galveston, Texas 77550 (US) BAUGHN, Mariah, R. San Leandro, CA 94577 (US) LU, Dyung, Aina, M. San Jose, CA 95123 (US) YUE, Henry Sunnyvale, CA 94087 (US) GRAUL, Richard, C. San Francisco, CA 94121 (US) LU, Yan Mountain View, California 94040 (US) DING, Li Palo Alto, CA 94306 (US) TRIBOULEY, Catherine, M. San Francisco, CA 94107 (US) TANG, Y., Tom San Jose, CA 95118 (US) GANDHI, Ameena, R. San Francisco, CA 94118 (US) THORNTON, Michael Oakland, California 94605 (US) (74) Representative: Wright, Simon Mark  J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5JJ London WC1R 5JJ (GB)