(19)

(11)

EP 1 341 549 A2

(12)

(88) Date of publication A3: 01.05.2003 (43) Date of publication: 10.09.2003 Bulletin 2003/37 (21) Application number: 01990699.9 (22) Date of filing: 06.11.2001

(51) International Patent Classification (IPC)7: A61K 38/09, A61P 35/00 (86) International application number: PCT/US0143/847 (87) International publication number: WO 0203/9995 (23.05.2002 Gazette 2002/21)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 16.11.2000 US 714605 (71) Applicant: PHARMACIA & UP JOHN COMPANY Peapack, NJ 07977 (US)	(72) Inventor: PURANDARE, Dinesh Branchburg, NJ 08876 (US) (74) Representative: Longoni, Alessandra  Pharmacia Italia S.p.A.,Patent Department,Viale Pasteur 10 20014 Nerviano (MI) 20014 Nerviano (MI) (IT)