(19)

(11)

EP 1 343 796 A2

(12)

(88) Date of publication A3: 23.01.2003 (43) Date of publication: 17.09.2003 Bulletin 2003/38 (21) Application number: 01985647.5 (22) Date of filing: 23.10.2001

(51) International Patent Classification (IPC)7: C07H 1/00 (86) International application number: PCT/US0151/175 (87) International publication number: WO 0203/4760 (02.05.2002 Gazette 2002/18)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 23.10.2000 US 242427 P (71) Applicant: SmithKline Beecham Corporation Philadelphia, PA 19103 (US)	(72) Inventors: BONDINELL, William, E. King of Prussia, PA 19406 (US) NEEB, Michael, J. King of Prussia, PA 19406 (US) (74) Representative: Walker, Ralph Francis, Dr. et al GlaxoSmithKlineCorporate Intellectual Property (CN9.25.1)980 Great West Road Brentford, Middlesex TW8 9GS Brentford, Middlesex TW8 9GS (GB)