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EP 1 345 891 A1

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(43) Date of publication: 24.09.2003 Bulletin 2003/39 (21) Application number: 01996529.2 (22) Date of filing: 15.11.2001

(51) International Patent Classification (IPC)7: C07C 275/28, C07C 275/34, C07C 275/32, C07C 275/40, C07D 319/08, C07D 319/20, C07D 209/48, C07D 271/06, C07D 333/36, C07D 257/04, A61K 31/197, A61K 31/41, A61P 3/10, A61P 3/04 (86) International application number: PCT/DK0100/760 (87) International publication number: WO 0204/0446 (23.05.2002 Gazette 2002/21)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 17.11.2000 DK 200001733 (71) Applicant: Novo Nordisk A/S 2880 Bagsvaerd (DK)	(72) Inventors: JORGENSEN, Anker, Steen DK-2100 Copenhagen (DK) MADSEN, Peter DK-2880 Bagsvaerd (DK)