(19)

(11)

EP 1 346 048 A1

(12)

(43) Date of publication: 24.09.2003 Bulletin 2003/39 (21) Application number: 01949677.7 (22) Date of filing: 11.07.2001

(51) International Patent Classification (IPC)7: C12N 15/30, C12R 1/35, C07K 14/30, C12Q 1/68 (86) International application number: PCT/GB0103/128 (87) International publication number: WO 0300/6653 (23.01.2003 Gazette 2003/04)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR (30) Priority: 11.07.2000 GB 0017073 (71) Applicant: Windsor, Helena Reigate,Surrey RH2 9BY (GB)	(72) Inventor: Windsor, Helena Reigate,Surrey RH2 9BY (GB) (74) Representative: Downing, Michael Philip et al Fry Heath & Spence LLP,The Gables,Massett Road Horley,Surrey RH6 7DQ Horley,Surrey RH6 7DQ (GB)