(19)
(11) EP 1 349 548 A2

(12)

(88) Date of publication A3:
12.09.2002

(43) Date of publication:
08.10.2003 Bulletin 2003/41

(21) Application number: 01994350.5

(22) Date of filing: 28.12.2001
(51) International Patent Classification (IPC)7A61K 31/34, A61K 31/44, A61K 31/425
(86) International application number:
PCT/US0149/638
(87) International publication number:
WO 0205/3099 (11.07.2002 Gazette 2002/28)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 03.01.2001 US 259441 P

(71) Applicant: Merck & Co., Inc.
Rahway,New Jersey 07065-0907 (US)

(72) Inventors:
  • HARTMAN, George, D.
    Rahway, NJ 07065-0907 (US)
  • RODAN, Sevgi, B.
    Rahway, NJ 07065-0907 (US)
  • RODAN, Gideon, A.
    Rahway, NJ 07065-0907 (US)

(74) Representative: Cole, William Gwyn et al
European Patent Department,Merck & Co., Inc.,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) METHODS AND COMPOSITIONS FOR TREATING PERIODONTAL DISEASE