PHENYLETHENYL OR PHENYLETHINYL DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS

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EP 1 349 839 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	22.06.2005 Bulletin 2005/25

(45)	Mention of the grant of the patent:
	09.02.2005 Bulletin 2005/06

(21)	Application number: 01990437.4

(22)	Date of filing: 26.11.2001

(51)	International Patent Classification (IPC)⁷: C07D 233/90, A61K 31/4164, C07D 413/04, A61P 25/28

(86)	International application number:
	PCT/EP2001/013714

(87)	International publication number:
	WO 2002/046166 (13.06.2002 Gazette 2002/24)

(54)	PHENYLETHENYL OR PHENYLETHINYL DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS PHENYLETHENYL- ODER PHENYLETHINYLDERIVATE ALS GLUTAMATREZEPTORANTAGONISTEN DERIVES PHENYLETHENYLE OU PHENYLETHINYLE SERVANT D'ANTAGONISTES DE RECEPTEUR DE GLUTAMATE

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
	Designated Extension States:
	LT LV MK RO SI

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Priority:

04.12.2000 EP 00126615

(43)	Date of publication of application:
	08.10.2003 Bulletin 2003/41

(73)	Proprietor: F. Hoffmann-La Roche AG
	4070 Basel (CH)

(72)	Inventors:
	MUTEL, Vincent F-68350 Brunstatt (FR) PETERS, Jens-Uwe 79639 Grenzach-Wyhlen (DE) WICHMANN, Juergen 79585 Steinen (DE)

(74)	Representative: Heiroth, Ulrike Hildegard et al
	124 Grenzacherstrasse 4070 Basle 4070 Basle (CH)

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References cited: :

WO-A-01/16121
WO-A-99/08678

WO-A-99/02497
DE-A- 2 035 905

A. SHAFIEE ET AL.: "Synthesis of 2-(2-arylethyl)-1-methylimidazoles" J. HETEROCYCL. CHEM., vol. 33, no. 3, 1996, pages 671-673, XP001069539
T. SAKAMOTO ET AL.: "Palladium-catalyzed reactions of terminal acetylenes and olefins with halo-1,3-azoles" CHEM. PHARM. BULL., vol. 35, no. 2, 1987, pages 823-828, XP001068936 cited in the application
A. SHAFIEE ET AL.: "Synthesis of 2-(2-arylethyl)imidazoles" J. HETEROCYCLIC CHEM., vol. 35, no. 3, 1998, pages 607-610, XP001069546
DATABASE CROSSFIRE BEILSTEIN [Online] Beilstein Institut zur Förderung der Chemischen Wissenschaften, Frankfurt am Main, DE; Database accession no. 8615795 XP002197389 & IVANOVA ET AL.: CHEM. HETEROCYCL. COMP. (ENGL. TRANSL.), vol. 36, no. 2, 2000, pages 262-264,
DATABASE CROSSFIRE BEILSTEIN [Online] Beilstein Institut zur Förderung der Chemischen Wissenschaften, Frankfurt am Main, DE; Database accession no. 141661 XP002197390 & WADSWORTH: J. CHEM. SOC., vol. 57, 1890, page 11
DATABASE CROSSFIRE BEILSTEIN [Online] Beilstein Institut zur Förderung der Chemischen Wissenschaften, Frankfurt am Main, DE; Database accession no. 3960 XP002197391 & CORNFORTH; COOKSON: J. CHEM. SOC., - 1952 pages 1085-1087,
CHEMICAL ABSTRACTS, vol. 78, no. 3, 1973 Columbus, Ohio, US; abstract no. 11433e, page 10; XP002197388 & W. ROSS: "Antiparasitic nitroimidazoles" J. MED. CHEM., vol. 15, no. 10, 1972, pages 1035-40,
MILLER R D ET AL: "SUBSTITUTED AZOLE DERIVATIVES AS NONLINEAR OPTICAL CHROMOPHORES" CHEMISTRY OF MATERIALS, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US, vol. 6, no. 7, 1994, pages 1023-1032, XP002028006 ISSN: 0897-4756 cited in the application


	Remarks:
	The file contains technical information submitted after the application was filed and not included in this specification

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).