(19)
(11)
EP 1 350 115 A2
(12)
(88)
Date of publication A3:
31.07.2003
(43)
Date of publication:
08.10.2003
Bulletin 2003/41
(21)
Application number:
01939635.7
(22)
Date of filing:
30.05.2001
(51)
International Patent Classification (IPC)
7
:
G01N
33/68
(86)
International application number:
PCT/US0117/351
(87)
International publication number:
WO 0109/2990
(
06.12.2001
Gazette 2001/49)
(84)
Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
(30)
Priority:
01.06.2000
US 208628 P
12.07.2000
US 614735
(71)
Applicant:
Variagenics, Inc.
Cambridge, MA 02139 (US)
(72)
Inventors:
CHASMAN, Daniel I.
Somerville, MA 02144 (US)
ADAMS, R., Mark
Natick, MA 01760 (US)
(74)
Representative:
Grund, Martin, Dr. et al
Dr. Volker Vossius,Patentanwaltskanzlei,Geibelstrasse 6
81679 München
81679 München (DE)
(54)
STRUCTURE-BASED METHODS FOR ASSESSING AMINO ACID VARIANCES