SUBSTITUTED 2-ARYL-4-ARYLAMINOPYRIMIDINES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF - Patent 1351691

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EP 1 351 691 A1

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(43)	Date of publication:
	15.10.2003 Bulletin 2003/42

(21)	Application number: 01990048.9

(22)	Date of filing: 12.12.2001

(51)	International Patent Classification (IPC)⁷: A61K 31/50, A61K 31/53, A61K 31/505

(86)	International application number:
	PCT/US0147/498

(87)	International publication number:
	WO 0204/7690 (20.06.2002 Gazette 2002/25)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

12.12.2000 US 254581 P

(71)	Applicant: Cytovia, Inc.
	San Diego, CA 92121 (US)

(72)	Inventors:
	CAI, Sui, Xiong San Diego, CA 92130 (US) DREWE, John, A. Carlsbad, CA 92009 (US) NGUYEN, Bao San Diego, CA 92126 (US) REDDY, P, Sanjeeva San Diego, CA 92130 (US) PERVIN, Azra San Marcos, CA 92069 (US)

(74)	Representative: Adams, Harvey Vaughan John et al
	Mathys & Squire,100 Gray's Inn Road London WC1X 8AL London WC1X 8AL (GB)

(54)	SUBSTITUTED 2-ARYL-4-ARYLAMINOPYRIMIDINES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF