(19)
(11) EP 1 356 053 A2

(12)

(88) Date of publication A3:
10.04.2003

(43) Date of publication:
29.10.2003 Bulletin 2003/44

(21) Application number: 02718823.4

(22) Date of filing: 09.01.2002
(51) International Patent Classification (IPC)7C12N 15/25
(86) International application number:
PCT/US0200/714
(87) International publication number:
WO 0205/5688 (18.07.2002 Gazette 2002/29)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 10.01.2001 US 260733 P

(71) Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
Rockville, MD 20852 (US)

(72) Inventors:
  • FOJO, Antonio, Tito
    Rockville, MD 20850 (US)
  • BATES, Susan, Elaine
    Bethesda, MD 20814 (US)

(74) Representative: Gowshall, Jonathan Vallance 
FORRESTER & BOEHMERTPettenkoferstrasse 20-22
80336 München
80336 München (DE)

   


(54) HISTONE DEACETYLASE INHIBITORS IN DIAGNOSIS AND TREATMENT OF THYROID NEOPLASMS