(19)
(11) EP 1 362 918 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
05.08.2009 Bulletin 2009/32

(45) Mention of the grant of the patent:
19.11.2008 Bulletin 2008/47

(21) Application number: 03016618.5

(22) Date of filing: 25.06.1999
(51) International Patent Classification (IPC): 
C12N 15/867(2006.01)
C12N 15/87(2006.01)
 C07K 14/78(2006.01)

(54)

Gene transfer methods with retroviruses

Methoden für Gentransfer mit Retroviren

Méthode de transfert génique par des rétrovirus

(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 01.07.1998 JP 18624098
04.03.1999 JP 5691599

(43) Date of publication of application:
19.11.2003 Bulletin 2003/47

(62) Application number of the earlier application in accordance with Art. 76 EPC:
99926821.2 / 1094114

(73) Proprietor: TAKARA BIO INC.
Otsu-shi, Shiga (JP)

(72) Inventors:
  • Ueno, Mitsuhiro
    Kusatsu-shi, Shiga 525-0025 (JP)
  • Yoshioka, Hirofumi
    Ritto-shi, Shiga 520-3026 (JP)
  • Konishi, Haruko, 407, Gurankoto-Rakuvo
    Kyoto-shi, Kyoto 600-8853 (JP)
  • Hashino, Kimikazu, 27-3, Akeno-cho
    Osaka 596-0082 (JP)
  • Morishita, Mio
    Otsu-shi, Shiga 520-0246 (JP)
  • Chono, Hideto,
    Shiga 524-0036 (JP)
  • Miyamura, Tsuyoshi, 103, Hamoparesu-Kusatsu 12-1
    kusatsu-shi, Shiga 525-0025 (JP)
  • Sano, Mutsumi, 615.Rumon-Nishiotsu
    Shiga 520-0014 (JP)
  • Asada, Kiyozo
    Shiga 520-3333 (JP)
  • Fujinaga, Kei
    Sapporo-shi, Hokaido 0640-0941 (JP)
  • Kato, Ikunoshin
    Kyoto 611-0028 (JP)

(74) Representative: Schnappauf, Georg et al
Dr. Volker Vossius Patent- und Rechtsanwaltskanzlei Geibelstrasse 6
81679 München
81679 München (DE)


(56) References cited: : 
EP-A- 0 531 733
WO-A-97/18318
 WO-A-92/00524
US-A- 5 656 456
   
  • PATENT ABSTRACTS OF JAPAN vol. 1997, no. 04, 30 April 1997 (1997-04-30) -& JP 08 317785 A (KANAGAWA KAGAKU GIJUTSU AKAD), 3 December 1996 (1996-12-03)
  • SAPPEY ET AL: "Iron chelation decreases NF-kB and HIV type 1 activation due to oxidative stress" AIDS RESEARCH AND HUMAN RETROVIRUSES, MARY ANN LIEBERT, US, vol. 11, no. 9, 1995, pages 1049-1061, XP002104523 ISSN: 0889-2229
  • KAPTEIN L.C.M. ET AL: 'Optimized conditions for the production of recombinant amphotropic retroviral vector preparations.' GENE THERAPY vol. 4, 1997, pages 172 - 176
  • SANYAL ET AL: 'Increased transduction into early human cord blood progenitor cells by centrifugation enhanced transduction in fibronectin fragment coated tubes.' BLOOD, SUPPL 1 PART 1-2 vol. 92, no. 10, 15 November 1999, page 466A
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).