(19)
(11) EP 1 363 638 A2

(12)

(88) Date of publication A3:
25.09.2003

(43) Date of publication:
26.11.2003 Bulletin 2003/48

(21) Application number: 02714918.6

(22) Date of filing: 31.01.2002
(51) International Patent Classification (IPC)7A61K 31/505, A61K 31/495, A61K 31/50, A61K 31/535, A61K 31/40, A61K 31/47, A61K 31/44, A61K 31/425, A61K 31/42, A61K 31/415, A61P 25/00, C07D 209/02, C07D 209/82, C07D 215/38, C07D 231/56, C07D 239/02, C07D 261/06, C07D 401/00, C07D 403/02, C07D 405/00, C07D 413/00
(86) International application number:
PCT/US0204/608
(87) International publication number:
WO 0206/0392 (08.08.2002 Gazette 2002/32)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 31.01.2001 US 775341

(71) Applicant: Synaptic Pharmaceutical Corporation
Paramus, NJ 07652 (US)

(72) Inventors:
  • BLACKBURN, Thomas P.
    Hoboken, NJ 07030 (US)
  • KONKEL, Michael
    Garfield, NJ 07026 (US)
  • BOTEJU, Lakmal W.
    Cedar, NJ 07009 (US)
  • TALISMAN, Ian Jamie
    New York, NY 10024 (US)
  • WETZEL, John M.
    Fairlawn, NJ 07410 (US)
  • PACKIARAJAN, Mathivanan
    Saddle Brook, NJ 07663 (US)
  • CHEN, Heidi
    Wyckoff, NJ 07481 (US)
  • JIMENEZ, Hermo
    Hackensack, NJ 07601 (US)
  • LAGU, Bharat
    Belle Meade, NJ 08502 (US)
  • LIM, Kitae
    New York, NY 10014 (US)
  • NOBLE, Stewart
    Wheeling, IL 60090 (US)

(74) Representative: VOSSIUS & PARTNER 
Siebertstrasse 4
81675 München
81675 München (DE)

   


(54) USE OF GAL3 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF DEPRESSION AND/OR ANXIETY AND COMPOUNDS USEFUL IN SUCH METHODS