(19)

(11)

EP 1 363 664 A2

(12)

(88) Date of publication A3: 03.01.2003 (43) Date of publication: 26.11.2003 Bulletin 2003/48 (21) Application number: 02700174.2 (22) Date of filing: 19.02.2002

(51) International Patent Classification (IPC)7: A61K 39/385, A61K 47/48 (86) International application number: PCT/DK0200/112 (87) International publication number: WO 0206/6056 (29.08.2002 Gazette 2002/35)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 19.02.2001 WO PCT/DK01/00113 20.02.2001 US 785215 20.08.2001 DK 200101231 22.10.2001 US 337543 P (71) Applicant: Pharmexa A/S 2970 Horsholm (DK)	(72) Inventors: NIELSEN, Klaus Gregorius,c/o M & E Biotech A/S DK-2970 Horsholm (DK) KOEFOED, Peter,c/o Pharmexa A/S DK-2970 Horsholm (DK) (74) Representative: Inspicos A/S  Böge Allé 3,P.O. Box 45 2970 Hörsholm 2970 Hörsholm (DK)