(19)

(11)

EP 1 363 675 A2

(12)

(88) Date of publication A3: 27.02.2003 (43) Date of publication: 26.11.2003 Bulletin 2003/48 (21) Application number: 02716783.2 (22) Date of filing: 15.02.2002

(51) International Patent Classification (IPC)7: A61K 47/48, C12N 15/87, C07K 7/08, C07K 14/00 (86) International application number: PCT/EP0201/646 (87) International publication number: WO 0207/4794 (26.09.2002 Gazette 2002/39)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 27.02.2001 EP 01440049 23.03.2001 US 277982 P 15.05.2001 EP 01440133 25.05.2001 US 293187 P (71) Applicant: TRANSGENE S.A. 67082 Strasbourg Cédex (FR)	(72) Inventors: RITTNER, Karola F-67000 Strasbourg (FR) JACOBS, Eric F-67140 Stotzheim (FR) (74) Representative: VOSSIUS & PARTNER  Siebertstrasse 4 81675 München 81675 München (DE)