(19)
(11) EP 1 363 993 A2

(12)

(88) Date of publication A3:
10.10.2002

(43) Date of publication:
26.11.2003 Bulletin 2003/48

(21) Application number: 02714815.4

(22) Date of filing: 01.02.2002
(51) International Patent Classification (IPC)7C12N 1/21, C12N 5/10, C12N 9/12, C12N 15/54, C07D 487/04, A61K 31/4745
(86) International application number:
PCT/US0203/060
(87) International publication number:
WO 0206/0386 (08.08.2002 Gazette 2002/32)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 01.02.2001 US 265853 P
27.09.2001 US 965977

(71) Applicant: Bristol-Myers Squibb Company
Princeton, NJ 08543-4000 (US)

(72) Inventors:
  • BURKE, James, R.
    Holland, PA 18966 (US)
  • NADLER, Steven
    Princeton, NJ 08540 (US)
  • QIU, Yuping
    Windsor, CT 06095 (US)
  • TOWNSEND, Robert, M.
    Boothwyn, PA 19061 (US)
  • ZUSI, Fred, Christopher
    Hamden, CT 06514 (US)

(74) Representative: VOSSIUS & PARTNER 
Siebertstrasse 4
81675 München
81675 München (DE)

   


(54) METHODS OF TREATING INFLAMMATORY AND IMMUNE DISEASES USING INHIBITORS OF I$g(k)B KINASE (IKK)