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(11)

EP 1 364 007 A1

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(43) Date of publication: 26.11.2003 Bulletin 2003/48 (21) Application number: 01907280.0 (22) Date of filing: 23.02.2001

(51) International Patent Classification (IPC)7: C12N 15/10, C12N 15/12, C12N 15/85, C12N 5/10, C07K 14/47, C12Q 1/68 (86) International application number: PCT/CA0100/205 (87) International publication number: WO 0203/8755 (16.05.2002 Gazette 2002/20)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (71) Applicants: Jefferies, Wilfried A. Surrey,British Columbia V6T 2C2 (CA) Choi, Kyung Bok Burnaby,British Columbia V5H 4R8 (CA) Cheng, Nick Coquitlam,British Columbia V3E 2W8 (CA) Payne, Kendra Vancouver,British Columbia V6J 1N3 (CA) Ujiie, Maki Vancouver,British Columbia V6M 2G3 (CA)

(72) Inventors: Jefferies, Wilfried A. Surrey,British Columbia V6T 2C2 (CA) Choi, Kyung Bok Burnaby,British Columbia V5H 4R8 (CA) Cheng, Nick Coquitlam,British Columbia V3E 2W8 (CA) Payne, Kendra Vancouver,British Columbia V6J 1N3 (CA) Ujiie, Maki Vancouver,British Columbia V6M 2G3 (CA) (74) Representative: Gowshall, Jonathan Vallance  FORRESTER & BOEHMERTPettenkoferstrasse 20-22 80336 München 80336 München (DE)