(19)

(11)

EP 1 365 753 A2

(12)

(88) Date of publication A3: 28.08.2003 (43) Date of publication: 03.12.2003 Bulletin 2003/49 (21) Application number: 02702137.7 (22) Date of filing: 04.02.2002

(51) International Patent Classification (IPC)7: A61K 31/00 (86) International application number: PCT/US0203/201 (87) International publication number: WO 0206/2369 (15.08.2002 Gazette 2002/33)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 02.02.2001 US 265955 P (71) Applicant: Pharmacia Corporation St. Louis, MO 63167 (US)	(72) Inventor: MASFERRER, Jaime, L. Ballwin, MO 63011 (US) (74) Representative: Albrecht, Thomas, Dr.  Kraus & Weisert,Thomas-Wimmer-Ring 15 80539 München 80539 München (DE)