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(11)

EP 1 365 761 A1

(12)

(43) Date of publication: 03.12.2003 Bulletin 2003/49 (21) Application number: 00989288.6 (22) Date of filing: 18.12.2000

(51) International Patent Classification (IPC)7: A61K 31/44, A61K 31/55, A61P 9/00, A61P 9/02, A61P 9/04, A61P 9/10, A61P 9/12, A61P 11/00, A61P 27/00, A61P 43/00 // A61K31:44, A61K31:55 (86) International application number: PCT/US0034/246 (87) International publication number: WO 0204/9645 (27.06.2002 Gazette 2002/26)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (71) Applicant: Novartis AG 4056 Basel (CH)	(72) Inventors: DALEY, William, Lionel Morris Plains, NJ 07950 (US) WEBB, Randy, Lee Flemington, NJ 08822 (US) (74) Representative: Grubb, Philip William  Novartis AG,Corporate Intellectual Property 4002 Basel 4002 Basel (CH)