(19)
(11) EP 1 366 175 A2

(12)

(88) Date of publication A3:
18.09.2003

(43) Date of publication:
03.12.2003 Bulletin 2003/49

(21) Application number: 01988344.6

(22) Date of filing: 18.12.2001
(51) International Patent Classification (IPC)7C12N 15/62, C12N 15/15, C07K 14/81, A61K 38/55, A61K 38/57
(86) International application number:
PCT/US0149/256
(87) International publication number:
WO 0205/0287 (27.06.2002 Gazette 2002/26)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 18.12.2000 US 256699 P
20.11.2001 US 331966 P

(71) Applicant: Arriva Pharmaceuticals, Inc.
Alameda, CA 94501 (US)

(72) Inventors:
  • BARR, Philip, J.
    Oakland, CA 94619 (US)
  • GIBSON, Helen, L.
    Oakland, CA 94605 (US)
  • PEMBERTON, Philip
    SanMateo, CA 94402 (US)

(74) Representative: Roques, Sarah Elizabeth 
J.A. Kemp & Co.14 South SquareGray's Inn
London WC1R 5JJ
London WC1R 5JJ (GB)

   


(54) MULTIFUNCTIONAL PROTEASE INHIBITORS AND THEIR USE IN TREATMENT OF DISEASE