(19)

(11)

EP 1 368 055 A2

(12)

(88) Date of publication A3: 09.01.2003 (43) Date of publication: 10.12.2003 Bulletin 2003/50 (21) Application number: 02702232.6 (22) Date of filing: 07.03.2002

(51) International Patent Classification (IPC)7: A61K 38/26 (86) International application number: PCT/DK0200/142 (87) International publication number: WO 0206/9994 (12.09.2002 Gazette 2002/37)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 07.03.2001 US 800541 08.03.2001 WO PCT/DK01/00150 21.05.2001 DK 200100812 07.09.2001 US 949344 07.09.2001 DK 200101322 11.09.2001 DK 200101322 13.09.2001 US 951300 (71) Applicant: NOVO NORDISK A/S 2880 Bagsvaerd (DK)	(72) Inventors: KNUDSEN, Liselotte, Bjerre DK-2500 Valby (DK) WASSERMANN, Karsten DK-2820 Gentofte (DK) STURIS, Jeppe DK-3500 Vaerloese (DK) BRAND, Christian, Lehn DK-3450 Alleroed (DK) GODTFREDSEN, Carsten, Foged DK-2730 Herlev (DK) (74) Representative: Stahr, Pia et al Novo Nordisk A/S,Corporate Patents,Novo Allé 2880 Bagsvaerd 2880 Bagsvaerd (DK)