(19)

(11)

EP 1 368 376 A2

(12)

(88) Date of publication A3: 10.10.2002 (43) Date of publication: 10.12.2003 Bulletin 2003/50 (21) Application number: 02719729.2 (22) Date of filing: 25.01.2002

(51) International Patent Classification (IPC)7: C07K 14/47, C12N 15/12, C07K 16/18, C12Q 1/68 (86) International application number: PCT/EP0200/806 (87) International publication number: WO 0205/9149 (01.08.2002 Gazette 2002/31)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 26.01.2001 EP 01101800 (71) Applicant: Boehringer Ingelheim International GmbH 55216 Ingelheim (DE)	(72) Inventors: BEUG, Hartmut A-1140 Vienna (AT) HOFMANN, Johannes 61381 Köppern/Friedrichsdorf (DE) (74) Representative: Hammann, Heinz, Dr. et al c/o Boehringer Ingelheim GmbH,CD Patents 55216 Ingelheim am Rhein 55216 Ingelheim am Rhein (DE)