(19)

(11)

EP 1 368 484 A2

(12)

(88) Date of publication A3: 10.07.2003 (43) Date of publication: 10.12.2003 Bulletin 2003/50 (21) Application number: 01970858.5 (22) Date of filing: 14.09.2001

(51) International Patent Classification (IPC)7: C12N 15/82 (86) International application number: PCT/US0128/506 (87) International publication number: WO 0202/2675 (21.03.2002 Gazette 2002/12)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 15.09.2000 US 232778 P 22.06.2001 US 300183 P (71) Applicants: Syngenta Participations AG 4058 Basel (CH) UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL Chapel Hill,North Carolina 27599-4100 (US) Glazebrook, Jane San Diego, CA 92130 (US) Wang, Xun San Diego, CA 92121 (US) Dangl, Jeffrey L. Carrboro, NC 27510 (US) Eulgem, Thomas Carrboro, NC 27510 (US) Zhu, Tong San Diego, CA 92130 (US)

(72) Inventors: GLAZEBROOK, Jane San Diego, CA 92130 (US) WANG, Xun San Diego, CA 92121 (US) DANGL, Jeffrey L. Carrboro, NC 27510 (US) EULGEM, Thomas Carrboro, NC 27510 (US) ZHU, Tong San Diego, CA 92130 (US) (74) Representative: Dzieglewska, Hanna Eva  Frank B. Dehn & Co.,European Patent Attorneys,179 Queen Victoria Street London EC4V 4EL London EC4V 4EL (GB)