(19)

(11)

EP 1 370 295 A2

(12)

(88) Date of publication A3: 09.10.2003 (43) Date of publication: 17.12.2003 Bulletin 2003/51 (21) Application number: 01998364.2 (22) Date of filing: 27.11.2001

(51) International Patent Classification (IPC)7: A61K 47/48 (86) International application number: PCT/EP0113/800 (87) International publication number: WO 0204/3769 (06.06.2002 Gazette 2002/23)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 29.11.2000 US 253827 P 05.03.2001 GB 0105346 (71) Applicant: GENCELL S.A. 94400 Vitry sur Seine (FR)	(72) Inventors: HOFLAND, Hans Foster City, CA 94404 (US) LAMONS, Donald Emerald Hills, CA 94062 (US) MENG, Xiao-Ying Fremont, CA 94555 (US) (74) Representative: Lecca, Patricia et al Gencell SA,72-82, rue Léon Geffroy 94400 Vitry-sur-Seine 94400 Vitry-sur-Seine (FR)