(19)
(11) EP 1 370 546 A2

(12)

(88) Date of publication A3:
20.03.2003

(43) Date of publication:
17.12.2003 Bulletin 2003/51

(21) Application number: 02715079.6

(22) Date of filing: 11.03.2002
(51) International Patent Classification (IPC)7: C07D 307/79, C07D 307/81, C07D 333/54, C07D 405/06, C07D 405/04, C07D 409/04, C07D 407/04, C07D 417/04, A61K 31/343, A61K 31/4427, A61P 9/00, A61P 11/06, A61P 25/00, C07D 413/04, C07D 409/10, C07D 521/00, C07D 491/10, C07D 491/08
(86) International application number:
PCT/US0207/107
(87) International publication number:
WO 0207/4758 (26.09.2002 Gazette 2002/39)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 16.03.2001 US 810648
11.01.2002 US 44495
25.02.2002 US 81207

(71) Applicant: Abbott Laboratories
Abbott Park, IL 60064-6050 (US)

(72) Inventors:
  • COWART, Marlon, D.
    Round Lake Beach, IL 60073-4043 (US)
  • BENNANI, Youssef, L.
    Shaker Heights, OH 44122 (US)
  • FAGHIH, Ramin
    Lake Forest, IL 60045 (US)
  • GFESSER, Gregory, A.
    Waukegan, IL 60085 (US)
  • BLACK, Lawrence, A.
    Libertyville, IL 60048 (US)

(74) Representative: Modiano, Guido, Dr.-Ing. et al
Modiano, Josif, Pisanty & Staub,Baaderstrasse 3
80469 München
80469 München (DE)

   


(54) NOVEL AMINES AS HISTAMINE-3 RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS