(19)

(11)

EP 1 373 166 A2

(12)

(88) Date of publication A3: 12.12.2002 (43) Date of publication: 02.01.2004 Bulletin 2004/01 (21) Application number: 02718304.5 (22) Date of filing: 04.04.2002

(51) International Patent Classification (IPC)7: C07B 35/02, A61K 31/424, A61P 25/00, C07B 43/04 (86) International application number: PCT/GB2002/001387 (87) International publication number: WO 2002/081414 (17.10.2002 Gazette 2002/42)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 06.04.2001 GB 0108775 (71) Applicant: Thomas Swan & Co. Ltd. County Durham DH8 7ND (GB)	(72) Inventors: ROSS, Stephen, KeithThomas Swan & Co. Ltd. ConsettCo Durham DH8 7ND (GB) MEEHAN, Nicola, JaneThomas Swan & Co Ltd ConsettCo Durham DH8 7ND (GB) POLIAKOFF, Martyn Nottingham NG7 2RD (GB) CARTER, Daniel, N. Nottingham NG7 2RD (GB) (74) Representative: Atkinson, Jonathan David Mark  Urquhart-Dykes & LordTower HouseMerrion Way Leeds LS2 8PA Leeds LS2 8PA (GB)