(19)
(11)
EP 1 373 307 A2
(12)
(88)
Date of publication A3:
24.07.2003
(43)
Date of publication:
02.01.2004
Bulletin 2004/01
(21)
Application number:
02757911.9
(22)
Date of filing:
01.04.2002
(51)
International Patent Classification (IPC)
7
:
C07K
14/00
,
C07K
11/00
,
C12N
9/00
(86)
International application number:
PCT/US2002/010116
(87)
International publication number:
WO 2002/079223
(
10.10.2002
Gazette 2002/41)
(84)
Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI
(30)
Priority:
31.03.2001
US 280624 P
(71)
Applicant:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Austin, TX 78701 (US)
(72)
Inventors:
PAUL, Sudhir
Missouri City, TX 77459 (US)
NISHIYAMA, Yasuhiro
Houston, TX 77059 (US)
(74)
Representative:
Cripps, Joanna Elizabeth et al
Mewburn EllisYork House23 Kingsway
London WC2B 6HP
London WC2B 6HP (GB)
(54)
COVALENTLY REACTIVE TRANSITION STATE ANALOGS AND METHODS OF USE THEREOF