(19)

(11)

EP 1 377 287 A2

(12)

(88) Date of publication A3: 21.11.2002 (43) Date of publication: 07.01.2004 Bulletin 2004/02 (21) Application number: 02719009.9 (22) Date of filing: 15.02.2002

(51) International Patent Classification (IPC)7: A61K 31/40, A61K 31/35, A61K 35/78, A61K 39/385 (86) International application number: PCT/US2002/004764 (87) International publication number: WO 2002/076381 (03.10.2002 Gazette 2002/40)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 15.03.2001 US 276866 P 24.08.2001 US 938987 02.11.2001 US 53625 02.11.2001 WO PCT/US05/01131 04.12.2001 US 338721 P 10.12.2001 US 338969 P 10.12.2001 US 339033 P (71) Applicant: Proteotech, Inc. Kirkland, WA 98034 (US)	(72) Inventors: SNOW, Alan, D. Lynnwood, WA 98037 (US) CASTILLO, Geraldo, M. Seattle, WA 98178 (US) CHOI, Paula, Y. Bellevue, WA 98007 (US) NGUYEN, Beth, P. Renton, WA 98059 (US) (74) Representative: Lee, Nicholas John et al Kilburn & Strode,20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)