ISOXAXOLE DERIVATIVES AS INHIBITORS OF SRC AND OTHER PROTEIN KINASES - Patent 1377572

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EP 1 377 572 A1

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(43)	Date of publication:
	07.01.2004 Bulletin 2004/02

(21)	Application number: 02731356.8

(22)	Date of filing: 10.04.2002

(51)	International Patent Classification (IPC)⁷: C07D 413/14, A61K 31/505, C07D 413/04, C07D 417/14, A61K 31/4439, A61P 37/00, A61P 35/00

(86)	International application number:
	PCT/US2002/011609

(87)	International publication number:
	WO 2002/083668 (24.10.2002 Gazette 2002/43)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

10.04.2001 US 282935 P

(71)	Applicant: VERTEX PHARMACEUTICALS INCORPORATED
	Cambridge, MA 02139-4242 (US)

(72)	Inventor:
	HARRINGTON, Edmund South Boston, MA 02127 (US)

(74)	Representative: Cornish, Kristina Victoria Joy et al
	Kilburn & Strode,20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)

(54)	ISOXAXOLE DERIVATIVES AS INHIBITORS OF SRC AND OTHER PROTEIN KINASES