(19)

(11)

EP 1 377 668 A2

(12)

(88) Date of publication A3: 02.10.2003 (43) Date of publication: 07.01.2004 Bulletin 2004/02 (21) Application number: 02727508.0 (22) Date of filing: 30.03.2002

(51) International Patent Classification (IPC)7: C12N 15/70, C12N 7/00, C12N 7/04, A61K 48/00, A61K 39/245, C07K 14/03 (86) International application number: PCT/EP2002/003575 (87) International publication number: WO 2002/081712 (17.10.2002 Gazette 2002/42)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 03.04.2001 DE 10116594 (71) Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBH 55216 Ingelheim am Rhein (DE)	(72) Inventors: OSTERRIEDER, Nikolaus 17498 Wampen (DE) RUDOLPH, Jens 17498 Insel Riems (DE)