(19)

(11)

EP 1 379 666 A2

(12)

(88) Date of publication A3: 07.11.2002 (43) Date of publication: 14.01.2004 Bulletin 2004/03 (21) Application number: 02708250.2 (22) Date of filing: 08.03.2002

(51) International Patent Classification (IPC)7: C12N 15/80, C12N 9/12, C12N 15/54, C12N 1/15 (86) International application number: PCT/DK2002/000157 (87) International publication number: WO 2002/070721 (12.09.2002 Gazette 2002/37)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 08.03.2001 DK 200100395 12.03.2001 US 274650 P (71) Applicant: Arnau, José 2900 Hellerup (DK)	(72) Inventors: WOLFF, Anne, Mette DK-2820 Gentofte (DK) APPEL, Karen, Fuglede DK-2200 Copenhagen (DK) PETERSEN, Jesper, Breum DK-2720 Vanlose (DK) POULSEN, Ulla DK-2830 Virum (DK) ARNAU, José DK-2900 Hellerup (DK) JACOBSEN, Mette, Dorph DK-2800 Lyngby (DK) (74) Representative: HOEIBERG A/S  European Patent & Trademark AttorneysStore Kongensgade 59A 1264 Copenhagen K 1264 Copenhagen K (DK)