| (84) |
Designated Contracting States: |
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AT BE CH CY DE DK ES FI FR GR IE IT LI LU MC NL PT SE TR |
| (30) |
Priority: |
18.04.2001 GB 0109558
17.08.2001 GB 0120084
30.11.2001 US 998491
28.03.2002 GB 0207387
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| (43) |
Date of publication of application: |
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21.01.2004 Bulletin 2004/04 |
| (60) |
Divisional application: |
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10012535.0 |
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10154130.8 / 2228387 |
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10154171.2 |
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10160807.3 / 2228388 |
| (73) |
Proprietor: THE OPEN UNIVERSITY |
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Milton Keynes,
Buckinghamshire MK7 6BJ (GB) |
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| (72) |
Inventors: |
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- MILEUSNIC, Radmila,
c/o Dept. of Biological Sciences
Milton Keynes MK7 6AA (GB)
- ROSE, Steven Peter Russell,
c/o Dept. of Biological Sciences
Milton Keynes MK7 6AA (GB)
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| (74) |
Representative: W.P. Thompson & Co. |
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55 Drury Lane
London
WC2B 5SQ
London
WC2B 5SQ (GB) |
| (56) |
References cited: :
WO-A-94/09808
WO-A-97/04748
WO-A-98/21327
WO-A1-99/58564
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WO-A-97/00063
WO-A-98/09985
WO-A-99/67284
US-A- 5 958 883
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no. 10, 1994, pages 2357-2363, XP001031299 ISSN: 0014-2980
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BIND CELL SURFACE AND PROMOTE NEURITE EXTENSION" JOURNAL OF NEUROSCIENCE, NEW YORK,
NY, US, vol. 14, no. 9, 1994, pages 5461-5470, XP000920917 ISSN: 0270-6474
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Alzheimer's disease beta A4 amyloid precursor protein (APP) and its enhancement by
zinc(II)." JOURNAL OF MOLECULAR RECOGNITION, HEYDEN & SON LTD., vol. 8, no. 4, July
1995 (1995-07), pages 247-257, XP009005720 LONDON, GB ISSN: 0952-3499
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vol. 12, no. Supplement 11, 24 June 2000 (2000-06-24), page 314, XP009067508 & MEETING
OF THE FEDERATION OF EUROPEAN NEUROSCIENCE SOCIETIES; BRIGHTON, UK; JUNE 24-28, 2000
ISSN: 0953-816X
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protein, protects against memory loss caused by Abeta and acts as a cognitive enhancer"
EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 19, no. 7, April 2004 (2004-04), pages 1933-1938,
XP002383860 ISSN: 0953-816X
- MILEUSNIC R ET AL: "Amyloid precursor protein: from synaptic plasticity to Alzheimer's
disease." ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 1048, June 2005 (2005-06),
pages 149-165, XP002384155 ISSN: 0077-8923
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Y-2-receptor." EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 247, no. 3, 1997, pages 1019-1028,
XP001135256 ISSN: 0014-2956
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(1994), 39(6), 557-66, 1994, XP009005691
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0036-8075
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