(19)
(11) EP 1 381 680 A1

(12)

(43) Date of publication:
21.01.2004 Bulletin 2004/04

(21) Application number: 02743543.7

(22) Date of filing: 25.04.2002
(51) International Patent Classification (IPC)7: C12N 15/10, C12Q 1/68
(86) International application number:
PCT/IB2002/002778
(87) International publication number:
WO 2002/086121 (31.10.2002 Gazette 2002/44)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 25.04.2001 US 285998 P
25.04.2001 US 840861
25.04.2001 FR 0105573

(71) Applicant: Proteus
30000 Nîmes (FR)

(72) Inventors:
  • DUPRET, Daniel
    F-30420 Calvisson (FR)
  • LEFEVRE, Fabrice
    F-30900 Nîmes (FR)
  • MASSON, Jean-Michel
    F-31400 Toulouse (FR)

(74) Representative: Breese, Pierre 
3, avenue de l'Opéra
75001 Paris
75001 Paris (FR)

   


(54) TEMPLATE-MEDIATED, LIGATION-ORIENTED METHOD OF NONRANDOMLY SHUFFLING POLYNUCLEOTIDES