Process for the production of 2-(5-methyl-4-oxazolyl)acetates

(19)

(11)

EP 1 384 722 A8

(12)	CORRECTED EUROPEAN PATENT APPLICATION

(48)	Corrigendum issued on:
	08.09.2004 Bulletin 2004/37

(43)	Date of publication:
	28.01.2004 Bulletin 2004/05

(21)	Application number: 03020538.9

(22)	Date of filing: 19.03.1999

(51)	International Patent Classification (IPC)⁷: C07D 413/12, C07D 263/32, C07C 233/47

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

(30)

Priority:

30.03.1998 JP 10409898

(62)	Application number of the earlier application in accordance with Art. 76 EPC:
	99909293.5 / 0992503

(71)	Applicant: Japan Tobacco Inc.
	Tokyo 105-8422 (JP)

(72)	Inventors:
	Ando, Koji, 1-1, Murasaki-cho Takatsuki-shi Osaka 569-1125 (JP) Suzuki, Masanobu Tokyo 184-0004 (JP)

(74)	Representative: von Kreisler, Alek, Dipl.-Chem. et al
	Patentanwälte, von Kreisler-Selting-Werner, Bahnhofsvorplatz 1 (Deichmannhaus) 50667 Köln 50667 Köln (DE)


	Remarks:
	This application was filed on 17 - 09 - 2003 as a divisional application to the application mentioned under INID code 62.

(54)	Process for the production of 2-(5-methyl-4-oxazolyl)acetates

(57) The present invention relates to a novel method for producing a compound of the formula [11] wherein R is an optionally substituted aromatic hydrocarbon group, an optionally substituted alicyclic hydrocarbon group, an optionally substituted heterocyclic group or an optionally substituted condensed heterocyclic group, which is useful as a therapeutic agent for diabetes. The method of the present invention is an industrially utilizable method that enables efficient production of the objective compound [11] from β-methyl L-aspartate via an important intermediate compound [6] wherein R is as defined above, at high yield.