IN VIVO METHODS OF DETERMINING ACTIVITY OF RECEPTOR-TYPE KINASE INHIBITORS - Patent 1385983

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EP 1 385 983 A1

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(43)	Date of publication:
	04.02.2004 Bulletin 2004/06

(21)	Application number: 02719386.1

(22)	Date of filing: 29.03.2002

(51)	International Patent Classification (IPC)⁷: C12Q 1/00, C12Q 1/68, G01N 33/53, G01N 33/567, C07K 1/00, C07K 14/00, C07K 17/00, C07H 21/02, C07H 21/04

(86)	International application number:
	PCT/US2002/009758

(87)	International publication number:
	WO 2002/079498 (10.10.2002 Gazette 2002/41)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

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Priority:

02.04.2001 US 280771 P

(71)	Applicant: Merck & Co., Inc.
	Rahway,New Jersey 07065-0907 (US)

(72)	Inventors:
	THOMAS, Kenneth, A., JR. Rahway, NJ 07065-0907 (US) MAO, Xianzhi Rahway, NJ 07065-0907 (US) KENDALL, Richard, L. Rahway, NJ 07065-0908 (US)

(74)	Representative: Buchan, Gavin MacNicol
	Merck & Co., Inc.,European Patent Department,Terlings Park,Eastwick Road Harlow,Essex CM20 2QR Harlow,Essex CM20 2QR (GB)

(54)	IN VIVO METHODS OF DETERMINING ACTIVITY OF RECEPTOR-TYPE KINASE INHIBITORS