(19)
(11) EP 1 389 113 A1

(12)

(43) Date of publication:
18.02.2004 Bulletin 2004/08

(21) Application number: 02763956.6

(22) Date of filing: 05.04.2002
(51) International Patent Classification (IPC)7: A61K 31/506, A61P 37/08
(86) International application number:
PCT/US2002/010742
(87) International publication number:
WO 2002/080925 (17.10.2002 Gazette 2002/42)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 05.04.2001 GB 0108606

(71) Applicants:
  • Novartis AG
    4056 Basel (CH)
  • The Government of the United States of America, as represented by The Department of Veterans Affairs
    Washington, DC 20420 (US)
  • Oregon Health and Science University
    Portland,Oregon 97201-4753 (US)
  • Koike, Kenichi
    Matsumoto-Shi,Nagano 390-221 (JP)
  • Komiyama, Atsushi
    Matsumoto-Shi,Nagano 390-0316 (JP)

(72) Inventors:
  • HEINRICH, Michael
    Lake Oswego, OR 97035 (US)
  • KOIKE, Kenichi
    Matsumoto-Shi,Nagano Pref.390-0221 (JP)
  • KOMIYAMA, Atsushi
    Matsumoto-Shi,Nagano Pref. 390-0316 (JP)
  • NAKAJIMA, Motowo
    Ashiya-Shi,Hyogo Pref. 659-0012 (JP)
  • TAKEUCHI, Kouichi
    Matsumoto-Shi,Nagano Pref. 390-0804 (JP)

(74) Representative: Grubb, Philip William et al
Novartis AG,Corporate Intellectual Property
4002 Basel
4002 Basel (CH)

   


(54) USE OF N-PHENYL-2-PYRIMIDINEAMINE DERIVATIVEA AGAINST MAST CELL-BASED DISEASES LIKE ALLERGIC DISORDERS