(19)

(11)

EP 1 390 062 A2

(12)

(88) Date of publication A3: 27.02.2003 (43) Date of publication: 25.02.2004 Bulletin 2004/09 (21) Application number: 02731637.1 (22) Date of filing: 02.05.2002

(51) International Patent Classification (IPC)7: A61K 38/48, C12N 9/66, C12N 9/76, C12N 9/50, C12N 5/00, C12N 5/08 (86) International application number: PCT/US2002/013985 (87) International publication number: WO 2002/087511 (07.11.2002 Gazette 2002/45)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 02.05.2001 US 288256 P (71) Applicant: CENTER FOR BLOOD RESEARCH, INC. Boston, MA 02115 (US)	(72) Inventor: REMOLD-O'DONNELL, Eileen Brookline, MA 02445 (US) (74) Representative: Grund, Martin, Dr. et al Dr. Volker Vossius,Patentanwaltskanzlei,Geibelstrasse 6 81679 München 81679 München (DE)