(19)

(11)

EP 1 392 346 A2

(12)

(88) Date of publication A3: 20.11.2003 (43) Date of publication: 03.03.2004 Bulletin 2004/10 (21) Application number: 01941684.1 (22) Date of filing: 30.05.2001

(51) International Patent Classification (IPC)7: A61K 38/04 (86) International application number: PCT/US2001/017384 (87) International publication number: WO 2001/091700 (06.12.2001 Gazette 2001/49)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 30.05.2000 US 580156 30.05.2000 US 584001 30.05.2000 US 580110 30.05.2000 US 580893 (71) Applicant: Connective Tissue Imagineering LLC Visalia, CA 93291 (US)	(72) Inventors: MITTS, Thomas, F. Visalia, CA 93291 (US) SANDBERG, Lawrence, B. Murrieta,CA 92562 (US) JIMENEZ, Felipe, Jr. Loma Linda, CA 92357 (US) (74) Representative: McNally, Roisin et al Murgitroyd & Company165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)