(19)
(11) EP 1 397 383 A2

(12)

(88) Date of publication A3:
06.03.2003

(43) Date of publication:
17.03.2004 Bulletin 2004/12

(21) Application number: 01990229.5

(22) Date of filing: 13.12.2001
(51) International Patent Classification (IPC)7C07K 14/47, C12N 15/12, C12N 15/62, C07K 16/18, A61K 38/17, A61K 39/395, C12Q 1/68, G01N 33/68
(86) International application number:
PCT/US2001/048938
(87) International publication number:
WO 2003/000729 (03.01.2003 Gazette 2003/01)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 20.06.2001 WO PCT/US01/19692
09.07.2001 WO PCT/US01/21735

(71) Applicant: Genentech, Inc.
South San Francisco, CA 94080-4990 (US)

(72) Inventors:
  • GODDARD, Audrey
    San Francisco, CA 94131 (US)
  • WOOD, William I.
    Hillsborough, CA 94010 (US)
  • YE, Weilan
    Foster City, CA 94404 (US)
  • ZHANG, Zemin
    Foster City, CA 94404 (US)

(74) Representative: Denison, Christopher Marcus 
Mewburn EllisYork House23 Kingsway
London WC2B 6HP
London WC2B 6HP (GB)

   


(54) SECRETED POLYPEPTIDE AND THEIR USE IN THE TREATMENT OF BONE DISORDERS