(19)

(11)

EP 1 397 498 A1

(12)

(43) Date of publication: 17.03.2004 Bulletin 2004/12 (21) Application number: 02738948.5 (22) Date of filing: 16.05.2002

(51) International Patent Classification (IPC)7: C12N 15/86, C07K 14/08, C12N 7/04, A61K 39/00 (86) International application number: PCT/NL2002/000314 (87) International publication number: WO 2002/095040 (28.11.2002 Gazette 2002/48)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 21.05.2001 EP 01201921 (71) Applicant: ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V. 8219 PH Lelystad (NL)	(72) Inventor: VERHEIJE, Monique, Helene NL-8251 JC Dronten (NL) (74) Representative: Prins, Adrianus Willem et al Vereenigde,Nieuwe Parklaan 97 2587 BN Den Haag 2587 BN Den Haag (NL)