(19)

(11)

EP 1 397 680 A1

(12)

(43) Date of publication: 17.03.2004 Bulletin 2004/12 (21) Application number: 02725706.2 (22) Date of filing: 15.04.2002

(51) International Patent Classification (IPC)7: G01N 33/543 (86) International application number: PCT/US2002/012052 (87) International publication number: WO 2002/099430 (12.12.2002 Gazette 2002/50)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 30.05.2001 US 294861 P (71) Applicant: Disan, Inc. San Diego, CA 92150 (US)	(72) Inventor: SAND, Theodore,c/o Disan, Inc. Poway, CA 92064 (US) (74) Representative: Viering, Jentschura & Partner  Postfach 22 14 43 80504 München 80504 München (DE)