(19)

(11)

EP 1 401 269 A2

(12)

(88) Date of publication A3: 24.12.2003 (43) Date of publication: 31.03.2004 Bulletin 2004/14 (21) Application number: 02769713.5 (22) Date of filing: 13.05.2002

(51) International Patent Classification (IPC)7: A01K 67/00, A01K 67/027, C12N 15/00, G01N 33/00 (86) International application number: PCT/US2002/014876 (87) International publication number: WO 2002/092764 (21.11.2002 Gazette 2002/47)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 11.05.2001 US 290071 P 17.05.2001 US 291311 P 01.02.2002 US 353058 P 04.03.2002 US 361293 P (71) Applicant: Wyeth Madison, NJ 07928 (US)	(72) Inventors: BABIJ, Philip Dunstable, MA 01827 (US) BEX, Frederick, James, III Newtown Square, PA 19073 (US) BODINE, Peter, Van Nest Havertown, PA 19083 (US) (74) Representative: Duckworth, Timothy John  J.A. Kemp & Co.,14 South Square,Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)