(19)
(11) EP 1 404 676 A1

(12)

(43) Date of publication:
07.04.2004 Bulletin 2004/15

(21) Application number: 02740895.4

(22) Date of filing: 21.06.2002
(51) International Patent Classification (IPC)7C07D 487/04, A61K 31/505, A61P 29/00
(86) International application number:
PCT/GB2002/002835
(87) International publication number:
WO 2003/000695 (03.01.2003 Gazette 2003/01)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 23.06.2001 GB 0115393
28.06.2001 US 301678 P

(71) Applicant: AVENTIS PHARMACEUTICALS INC.
Bridgewater, New Jersey 08807 (US)

(72) Inventors:
  • COX, Paul Joseph,Aventis Pharma Ltd.
    West Malling,Kent ME19 4AH (GB)
  • MAJID, Tahir Nadeem,Aventis Pharma Limited
    Kings Hill,West Malling, Kent ME 19 4AH (GB)
  • AMENDOLA, Shelley
    Bedminster, NJ 07921 (US)
  • DEPRETS, Stephanie Daniele,Aventis Pharma Limited
    West Malling,Kent ME19 4AH (GB)
  • EDLIN, Chris,Aventis Pharma Limited
    West Malling,Kent ME19 4AH (GB)
  • PEDGRIFT, Brian Leslie,Aventis Pharma Limited
    West Malling,Kent ME19 4AH (GB)
  • HALLEY, Frank,Aventis Pharma Limited
    West Malling,Kent ME19 4AH (GB)
  • EDWARDS, Michael,Aventis Pharma Limited
    West Malling,Kent ME19 4AH (GB)
  • BAUDOIN, Bernard,Aventis Pharma Limited
    West Mall ing,Kent ME19 4AH (GB)
  • McLAY, Iain McFarlane
    Loughton, Essex IG 10 3DP (GB)
  • ALDOUS, Davis John,Aventis Pharma Limited
    West Malling,Kent ME19 4AH (GB)

(74) Representative: Then, Johann, Dr. 
Aventis Pharma Deutschland GmbHPatent- und LizenzabteilungGebäude K 801
65926 Frankfurt am Main
65926 Frankfurt am Main (DE)

   


(54) PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS