ATBECHDEDKESFRGBGRITLILUNLSEMCPTIE......FI....CY..TRBGCZEE....SK....................................JDIM360 Ver 2.15 (14 Jul 2008) - 2999001/0The file contains technical information submitted after the application was filed and not included in this specification1405912CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120121024W173deBibliographieenBibliographyfrBibliographieEP02745822.3200207042004010820060509jaenen200120691820010706JP2012102420124320040407200415201209052012362012012720121024201243C12P 21/02 20060101AFI20111102BHEP deGENETISCH MODIFIZIERTES ECARIN UND VERFAHREN ZU DESSEN HERSTELLUNGenGENETICALLY MODIFIED ECARIN AND PROCESS FOR PRODUCING THE SAMEfrECARINE GENETIQUEMENT MODIFIEE ET PROCEDE D'ELABORATIONWO-A-01/04146US-A- 5 602 034HOFMANN H ET AL: "BLOOD COAGULATION INDUCED BY THE VENOM OF BOTHROPS ATROX. I. IDENTIFICATION, PURIFICATION AND PROPERTIES OF A PROTHROMBIN ACTIVATOR" BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, vol. 26, no. 3, 1987, pages 772-780, XP001063236 ISSN: 0006-2960NOMURA M ET AL: "In vivo induction of cytotoxic T lymphocytes specific for a single epitope introduced into an unrelated molecule" JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 193, no. 1, 14 June 1996 (1996-06-14), pages 41-49, XP004020801 ISSN: 0022-1759RAKONJAC J ET AL: "Filamentous phage are released from the bacterial membrane by a two-step mechanism involving a short C-terminal fragment of pIII" JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 289, no. 5, 25 June 1999 (1999-06-25), pages 1253-1265, XP004451670 ISSN: 0022-2836NISHIDA S. ET AL.: 'cDNA cloning and deduced amino acid sequence of prothrombin activator (ecarin) from Kenyan Echis carinatus venom' BIOCHEMISTRY vol. 34, no. 5, 1995, pages 1771 - 1778, XP002159171MORITA T. ET AL.: 'Purification and properties of prothrombin activator from the venom of Echis carinatus' J. BIOCHEM. vol. 83, no. 2, 1978, pages 559 - 570, XP002955637BRIET E. ET AL.: 'Cleavage and activation of human prothrombin by Echis carinatus venom' THROMB. RES. vol. 27, no. 5, 1982, pages 591 - 600, XP002955638YAMAMOTO ET AL: JOURNAL OF CHROMATOGRAPHY, vol. 852, 1999, pages 37-41, XP004176667,20041118YONEMURA, Hiroshi1314-1, Yonnonishioki, Kawabe, KyokushimuraKikuchi-gun, Kumamoto 869-1298JPIMAMURA, Takayuki1314-1, Yonnonishioki, Kawabe, KyokushimuraKikuchi-gun, Kumamoto 869-1298JPNAKATAKE, Hiroshi1314-1, Yonnonishioki, Kawabe, KyokushimuraKikuchi-gun, Kumamoto 869-1298JPSOEJIMA, Kenji1314-1, Yonnonishioki, Kawabe, KyokushimuraKikuchi-gun, Kumamoto 869-1298JPNOZAKI, Chikateru1314-1, Yonnonishioki, Kawabe, KyokushimuraKikuchi-gun, Kumamoto 869-1298JPThe Chemo-Sero-Therapeutic Research Institute101308697H3276 EP S31-6-1 Okubo Kita-kuKumamoto-shi Kumamoto 860-8568JPVossius & Partner100751388Siebertstrasse 481675 MünchenDEATBEBGCHCYCZDEDKEEESFIFRGBGRIEITLILUMCNLPTSESKTRJP200200677020020704jaWO20030046472003011620030320040407200415