(19)
(11) EP 1 408 952 A1

(12)

(43) Date of publication:
21.04.2004 Bulletin 2004/17

(21) Application number: 02745640.9

(22) Date of filing: 16.07.2002
(51) International Patent Classification (IPC)7A61K 31/255, A61K 31/12
(86) International application number:
PCT/GB2002/003269
(87) International publication number:
WO 2003/007933 (30.01.2003 Gazette 2003/05)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 16.07.2001 GB 0117326

(71) Applicant: The University Court of The University of Aberdeen
Aberdeen,Grampian AB24 3FX (GB)

(72) Inventors:
  • WISCHIK, Claude M.,University of Aberdeen
    Aberdeen, Aberdeenshire AB25 2ZD (GB)
  • HORSLEY, David,University of Aberdeen
    Aberdeen, Aberdeenshire AB25 2ZD (GB)
  • RICKARD, Janet E.,University of Aberdeen
    Aberdeen, Aberdeenshire AB25 2ZD (GB)
  • HARRINGTON, Charles R.,University of Aberdeen
    Aberdeen, Aberdeenshire AB25 2ZD (GB)

(74) Representative: Kremer, Simon Mark et al
Mewburn Ellis,York House,23 Kingsway
London WC2B 6HP
London WC2B 6HP (GB)

   


(54) NAPTHOQUINONE DERIVATIVES AS INHIBITORS OF TAU AGGREGATION FOR THE TREATMENT OF ALZHEIMER'S AND RELATED NEURODEGENERATIVE DISORDERS